2-arm Branched PEG (SUNBRIGHT® GL2 Series)

2-arm activated branched PEGs can introduce two PEG chains into pharmaceutical substances by a single linkage and improve the pharmacokinetic profile of the pharmaceutical substances efficiently *.
2-arm activated branched PEGs have already been used in some marketed PEGylated drugs.
* Yulia V. et al., Bioconjugate Chem., 23, 1452(2012).

 

GS2 Type (NHS-ester PEG)

TS Type (NHS-carbonate PEG)

NP Type (p-Nitrophenyl Carbonate PEG)

AL3 Type (Aldehyde PEG)

PA Type (Aminopropyl PEG)

C2 MA Type (Maleimide PEG)

C5 MA Type (Maleimide PEG)

  1. 1
    2.
  2. 2
    3.
  3. 3
    4.
2arm branched PEG, -COO-pNP, Mw 80,000

Make to order

2arm branched PEG, -CONH(CH2)2-CHO, Mw 20,000
2arm branched PEG, -CONH(CH2)2-CHO, Mw 40,000
2arm branched PEG, -CONH(CH2)2-CHO, Mw 60,000
2arm branched PEG, -CONH(CH2)2-CHO, Mw 80,000

Make to order

2arm branched PEG, -(CH2)3-NH2, Mw 20,000   
2arm branched PEG, -(CH2)3-NH2, Mw 40,000
2arm branched PEG, -(CH2)3-NH2, Mw 60,000
2arm branched PEG, -(CH2)3-NH2, Mw 80,000
2arm branched PEG, -（CH2）3NHCO(CH2)2-MAL, Mw 20,000 /p>
  1. 1
    2.
  2. 2
    3.
  3. 3
    4.

Page Top