Phospholipids and Lipids

Phospholipids and Lipids for LNP and Liposome

Phospholipids and Lipids for LNP and Liposome

Using the world’s most advanced synthetic and purification technologies, NOF manufactures and supplies a series of highpurity lipid derivatives (COATSOME® Series) suitable for the formulation of lipid nanoparticles for nucleic acid and gene therapy drugs, liposomal and emulsion formulations for small molecule drugs.
Especially for the lipid nanoparticle formulation, We offer our proprietary ionizable lipids (COATSOME® SS Series) which enable efficient delivery of nucleic acids and low toxicity.
In addition, we can respond to requests from our customers with tailor-made synthesis of any lipids with the desired structures.

NOF’s Capabiliteis and Customer Advantages

cGMP Manufacturing Facility
Bulk phospholipids produced at our own validated facility under cGMP operation have been supplied worldwide for commercial drugs with long-standing reputations for quality and reliability for many years.

Drug Master Filings
NOF has already submitted more than 45 DMFs regarding various kinds of NOF manufactured phospholipids to the US FDA, so that customers can rely on our quality. We submit DMFs according to customers’ requests and development needs.
Custom Synthesis
Custom synthetic phospholipids and lipids can be produced at customer’s request.
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DOPG-Na 1,2-Dioleoyl-sn-glycero-3-phosphoglycerol, sodium salt
DMPA-Na 1,2-Dimyristoyl-sn-glycero-3-phosphatidic acid, sodium salt

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DPPA-Na 1,2-Dipalmitoyl-sn-glycero-3-phosphatidic acid, sodium salt

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DSPA-Na 1,2-Distearoyl-sn-glycero-3-phosphatidic acid, sodium salt

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DMPE 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine
DPPE 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
DSPE 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine
DOPE 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
DMPS-Na 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine, sodium salt
DPPS-Na 1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine, sodium salt
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