COATSOME CL-E8181TA (DOTMA)

Acronym: DOTMA
Chemical Name: 1,2-Dioleyloxy-3-trimethylammonium propane chloride
CAS#: 104872-42-6
Molecular weight: 670.6
Alkyl composition: 

DOTMA is a widely used cationic lipid enabling effective gene delivery in lipid-based formulations. DOTMA provides a positive charge to nanoparticle surfaces, promoting electrostatic interactions with negatively charged DNA and RNA, and enhancing nanoparticle-cell membrane interactions. This results in efficient transfection both in vitro and in vivo.