SUNBRIGHT® DSPE-020DB
DSPE-PEG-DBCO
Chemical Name: N-[(4-dibenzoazacyclooctyl-1,4-dioxobutyl) aminopropylpolyoxyethylene oxycarbonyl]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
Chemical Name: N-[(4-dibenzoazacyclooctyl-1,4-dioxobutyl) aminopropylpolyoxyethylene oxycarbonyl]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
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SUNBRIGHT DSPE-020DB is a functionalized PEG phospholipid designed to enhance the performance of lipid nanoparticle (LNP) and liposomal formulations in active targeting delivery systems. It features a DBCO group linked to the PEG chain of DSPE-PEG2000, providing a versatile platform for bioconjugation. The DBCO group enables site-specific conjugation with azide-containing molecules (such as peptides, antibodies, or other ligands) through copper-free click chemistry, forming a stable triazole linkage. This facilitates precise cellular targeting and enhances formulation versatility.