SUNBRIGHT® DSPE-050AZ2
DSPE-PEG-Azide
Chemical Name: N-[(5-azido-1-oxopentyl) aminopropylpolyoxyethylene oxycarbonyl]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
Chemical Name: N-[(5-azido-1-oxopentyl) aminopropylpolyoxyethylene oxycarbonyl]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
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SUNBRIGHT DSPE-050AZ2 is a functionalized PEG phospholipid designed to enhance performance in active targeting delivery systems. It features an azide group linked to the PEG chain of DSPE-PEG5000, providing a versatile platform for bioconjugation. The azide group enables site-specific conjugation with strained alkyne derivatives such as cyclooctyne (DBCO or BCN)-modified molecules (such as peptides, antibodies, or other ligands) through copper-free click chemistry, forming a stable triazole linkage. This facilitates efficient ligand conjugation, resulting in precise cellular targeting and enhanced formulation versatility.