SUNBRIGHT DSPE-050PA
Acronym: DSPE-PEG-NH2
Chemical Name: N-(Aminopropylpolyoxyethylene oxycarbonyl)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine
CAS#: 1251999-34-4
PEG chain Molecular weight: 5000
Alkyl composition: R1COO= C18:0, R2COO= C18:0
SUNBRIGHT DSPE-050PA is a functionalized PEG phospholipid designed to enhance the performance of lipid nanoparticle (LNP) and liposomal formulations in active targeting delivery systems. It features an amine group linked to the PEG chain of DSPE-PEG5000, enabling stable covalent bond formation with various activated groups (e.g., NHS esters, carboxylates via coupling reagents, or aldehydes under reductive amination), facilitating efficient ligand conjugation.