SUNBRIGHT® GM-034EX

DMG-PEG, PEG MW 3,400
Chemical Name: 1,2-Dimyristoyl-rac-glycero-3-methylpolyoxyethylene
CAS#: 160743-62-4
RCOO= C14:0

SUNBRIGHT GM-034EX (DMG-PEG3400) is an extremely high-purity PEG lipid designed to enhance the stability and efficiency of lipid nanoparticle (LNP) drug delivery systems. It features two C14:0 fatty acids (myristic acid) connected at the 1- and 2-positions of a glycerol backbone, and a polyethylene glycol (PEG) chain of 3,400 Da linked at the 3-position. By incorporating polyethylene glycol (PEG) into the surface of LNPs, it improves the stability and circulation time of LNPs in the bloodstream, facilitating efficient delivery of encapsulated therapeutic agents such as mRNA, siRNA, and other nucleic acids. GM-034EX is a key component in LNP formulations to improve the delivery and performance of nucleic acid-based therapies.